Paris MM, Hickey SM, Uscher MI, Shelton S, Olsen KD, McCracken. Infections of the central nervous system (CNS) can be divided into 2 broad categories: those primarily involving the meninges
Paris MM, Hickey SM, Uscher MI, Shelton S, Olsen KD, McCracken. Infections of the central nervous system (CNS) can be divided into 2 broad categories: those primarily involving the meninges ( meningitis ; see. Patients treated with corticosteroids had significantly lower rates of severe hearing loss (6.0 versus.3 any hearing loss (13.8 versus.0) and neurological sequelae (17.9 versus.6). The risk of dying or of developing complications is related to the age and general health of the patient, the causative pathogen, the severity and duration of illness at the time of presentation, and, occasionally, delays in the initiation of antibiotic therapy. Vancomycin is somewhat unreliable in its penetration into the cerebrospinal fluid. Pneumoniae ) treated with corticosteroids had a lower death rate (29.9 versus.0 while no effect on mortality was seen in patients with. No specific treatment exists for most of the viruses that cause meningitis ; therefore, management, for the most part, is supportive and includes. Key results, this review found that the corticosteroid dexamethasone did not significantly reduce the death rate (17.8 versus.9). Treatment for viral meningitis is mostly supportive. An unfavorable outcome (defined as moderate or greater disability as judged by the Glasgow Outcome Score) occurred in 15 of the treatment group vs 25 of the control group (relative risk.59,.03). Introduction, bacterial meningitis continues to result in substantial morbidity and mortality despite the availability of effective antimicrobial therapy. Syrogiannopoulos GA, Lourida AN, Theodoridou MC,. Rest, hydration, antipyretics, and pain or anti-inflammatory medications may be given. Lancet dosage Infect Dis 2004; 4:139143.