Sometimes these may be accompanied by involuntary movements of extremities and the trunk. While all can occur at relatively low doses, they occur more frequently and with greater severity at
higher doses. The ambulatory patient should be warned accordingly. Learn about, haldol Decanoate haloperidol Decanoate ) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related. Infants should not be nursed during drug treatment. Cautions, risk of sudden death, torsades de pointes, and prolonged QT interval from off-label IV administration of higher than recommended dose: monitor ECG if administering. Initial Therapy Conversion from oral haloperidol to haloperidol decanoate can be achieved by using an initial dose of haloperidol decanoate that is 10 to 20 times the previous daily dose in oral haloperidol equivalents. Learn about indications, dosage and how it is supplied for the drug. 5.2 Pharmacokinetic properties Haloperidol decanoate in solution is slowly released from the injection site and enters the systemic circulation, where it is hydrolysed by esterases to haloperidol. Patients with a history of a clinically significant low WBC or a drug-induced leukopenia/neutropenia should have their complete blood count (CBC) monitored frequently during the first few months of therapy and discontinuation of Haldol Decanoate should be considered at the first sign of a clinically. If indicated, adequate anticonvulsant therapy should be concomitantly maintained. For dosage and other prescribing information, see accompanying product literature. Haldol Decanoate (Haloperidol, decanoate ). The extrapyramidal reactions would be manifested by muscular weakness or rigidity and a generalized or localized tremor, as demonstrated by the akinetic or agitans types, respectively. Haldol Decanoate may impair the antiparkinsonian effects of levodopa. In case of severe extrapyramidal reactions, antiparkinson medication should be administered. Haldol Decanoate official prescribing information for healthcare professionals. Hyperthermia is often an early development sign of this syndrome. Contraindications, haldol (haloperidol) is contraindicated in severe toxic central nervous system depression or comatose states from any cause and in individuals who are hypersensitive to this drug or have Parkinson's disease. Since vast experience has accumulated with haldol, the adverse reactions are reported for that compound as well as for haloperidol decanoate.